Transfusion-Induced Iron Overload

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Transfusion-Induced Iron Overload

“In some patients, noticeably those with thalassemia major, sickle cell disease,myelodysplastic syndrome, aplastic anemia, hemolytic anemia, and refractory sideroblastic anemias, who may become transfusion-dependent and receive excess iron with each transfusion (that the body has no means to excrete), iron gradually accumulates in various tissues, causing morbidity and mortality.”


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